Co-Authors:
Polevaya, Y., Department of Applied Physics, Hebrew University of Jerusalem, 91904 Jerusalem, Israel
Ermolina, I., Department of Applied Physics, Hebrew University of Jerusalem, 91904 Jerusalem, Israel
Schlesinger, M., Hubert H. Humprey Ctr. Exp. Med. C., Hebrew University of Jerusalem, Hadassah Medical School, Jerusalem, Israel
Ginzburg, B.-Z., Plant Biophysical Laboratory, Institute of Life Science, Hebrew University of Jerusalem, Jerusalem, Israel
Feldman, Y., Department of Applied Physics, Hebrew University of Jerusalem, 91904 Jerusalem, Israel
Abstract:
The dielectric properties of human lymphocyte suspensions were studied by time domain dielectric spectroscopy (TDDS). Nine populations of malignant and normal lymphocytes were investigated. Analysis of the dielectric parameters of cell structural parts were performed in the framework of Maxwell-Wagner mixture formula and the double-shell model of cell. The specific capacitance of the cell membranes was estimated by the Hanai-Asami-Koisumi formula. It was shown that the dielectric permittivity, capacitance and conductivity values of cell membranes are higher for normal lymphocytes than for the malignant ones. The difference of the same parameters for normal B- and T-cells is also discussed. Copyright (C) 1999 Elsevier Science B.V.