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The RNA transcripts of Drosophila melanogaster src gene are differentially regulated during development
Year:
1986
Authors :
Segev, Orit
;
.
Volume :
867
Co-Authors:
Lev, Z., Department of Biology, Technion - Israel Institute of Technology, Haifa, 32000, Israel
Segev, O., Department of Biology, Technion - Israel Institute of Technology, Haifa, 32000, Israel
Facilitators :
From page:
144
To page:
151
(
Total pages:
8
)
Abstract:
This article describes the expression of the Drosophila src gene located at 64B. The gene extends over at least 7 kb of genomic DNA, and codes for three transcripts which are 3.0, 4.4 and 4.8 kb long. Their 3′ ends were identified and tentatively located on the physical map of the gene. All three transcripts are in the same polarity and contain the information required for translating the protein kinase domain common to all members of the src gene family. The Drosophila src transcripts are expressed in two different patterns during development. The 3.0 and 4.4 transcripts are abundant in unfertilized eggs and during embryogenesis. Their prevalence decreases under the limit of detection in the larval and pupal stages, and they reappear in adult flies. The larger 4.8 kb transcript is undetectable in unfertilized eggs. It starts accumulating between 2 and 5 h after fertilization, and is expressed continuously during development. © 1986.
Note:
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genetic engineering
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RNA
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More details
DOI :
10.1016/0167-4781(86)90074-6
Article number:
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
27769
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:33
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Scientific Publication
The RNA transcripts of Drosophila melanogaster src gene are differentially regulated during development
867
Lev, Z., Department of Biology, Technion - Israel Institute of Technology, Haifa, 32000, Israel
Segev, O., Department of Biology, Technion - Israel Institute of Technology, Haifa, 32000, Israel
The RNA transcripts of Drosophila melanogaster src gene are differentially regulated during development
This article describes the expression of the Drosophila src gene located at 64B. The gene extends over at least 7 kb of genomic DNA, and codes for three transcripts which are 3.0, 4.4 and 4.8 kb long. Their 3′ ends were identified and tentatively located on the physical map of the gene. All three transcripts are in the same polarity and contain the information required for translating the protein kinase domain common to all members of the src gene family. The Drosophila src transcripts are expressed in two different patterns during development. The 3.0 and 4.4 transcripts are abundant in unfertilized eggs and during embryogenesis. Their prevalence decreases under the limit of detection in the larval and pupal stages, and they reappear in adult flies. The larger 4.8 kb transcript is undetectable in unfertilized eggs. It starts accumulating between 2 and 5 h after fertilization, and is expressed continuously during development. © 1986.
Scientific Publication
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