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On the power of experimental designs for the detection of linkage between marker loci and quantitative loci in crosses between inbred lines
Year:
1976
Source of publication :
Theoretical and Applied Genetics
Authors :
Genizi, Abraham
;
.
Volume :
47
Co-Authors:
Soller, M., Department of Genetics, The Hebrew University, Jerusalem, Israel
Brody, T., Department of Genetics, The Hebrew University, Jerusalem, Israel
Genizi, A., Department of Statistics, Agricultural Research Organization, Rehovot, Israel
Facilitators :
From page:
35
To page:
39
(
Total pages:
5
)
Abstract:
The power of experiments aimed at detecting linkage between a quantitative locus and a marker locus, both segregating in the backross or F2 generation of a cross between two inbred lines, is examined. Given that the two lines are close to fixation for alternative alleles of both marker locus and quantitative locus, it is concluded that experiments involving a few thousand offspring should be able to detect close linkages involving quantitative loci (or groups of loci) having rather modest effects (i.e., that contribute, say, 1% of the total phenotypic variance in the F2). © 1976 Springer-Verlag.
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More details
DOI :
10.1007/BF00277402
Article number:
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
28769
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:41
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On the power of experimental designs for the detection of linkage between marker loci and quantitative loci in crosses between inbred lines
47
Soller, M., Department of Genetics, The Hebrew University, Jerusalem, Israel
Brody, T., Department of Genetics, The Hebrew University, Jerusalem, Israel
Genizi, A., Department of Statistics, Agricultural Research Organization, Rehovot, Israel
On the power of experimental designs for the detection of linkage between marker loci and quantitative loci in crosses between inbred lines
The power of experiments aimed at detecting linkage between a quantitative locus and a marker locus, both segregating in the backross or F2 generation of a cross between two inbred lines, is examined. Given that the two lines are close to fixation for alternative alleles of both marker locus and quantitative locus, it is concluded that experiments involving a few thousand offspring should be able to detect close linkages involving quantitative loci (or groups of loci) having rather modest effects (i.e., that contribute, say, 1% of the total phenotypic variance in the F2). © 1976 Springer-Verlag.
Scientific Publication
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