Stressed worms: Responding to the post-genomics era

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Stressed worms: Responding to the post-genomics era

Year: 

2005

Source of publication :

Molecular and Biochemical Parasitology

Authors :

Gal, Tali Z.

;

Glazer, Itamar

;

Koltai, Hinanit

.

Volume :

143

Co-Authors: 

Gal, T.Z., Department of Genomics, ARO, Volcani Center, Bet Dagan 50250, Israel
Glazer, I., Department of Nematology, ARO, Volcani Center, Bet Dagan 50250, Israel
Koltai, H., Department of Genomics, ARO, Volcani Center, Bet Dagan 50250, Israel

From page: 

1

To page: 

5

(

Total pages: 

5

)

Link :

Stressed worms: Responding to the post-genomics era

Abstract: 

Nematodes are among the most successful organisms in withstanding stress conditions associated with water loss, and viable individuals have been recovered from dry desert soils. Little is known about the biochemical and molecular events underpinning nematodes' physiological responses to dehydration. Post-genomics research in Caenorhabditis elegans may offer an opportunity to understand the stress response better. This review focuses on recent progress in understanding the molecular mechanisms of water-loss associated stress response in the model nematode C. elegans and in parasitic nematodes and discusses the scope for applying the knowledge and tools derived from a model organism for the study of wild, environmentally-adapted, parasitic nematodes, in the light of the emergence of genomics research of non-model organisms. © 2005 Elsevier B.V. All rights reserved.