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The nucleotide sequence of the rat cytoplasmic β-actin gene
Year:
1983
Source of publication :
Nucleic Acids Research
Authors :
Shani, Moshe
;
.
Volume :
11
Co-Authors:
Nudel, U., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Zakut, R., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Shani, M., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Neuman, S., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Levy, Z., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Yaffe, D., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Facilitators :
From page:
1759
To page:
1771
(
Total pages:
13
)
Abstract:
The nucleotide sequence of the rat β-actin gene was determined. The gene codes for a protein identical to the bovine β-actin. It has a large intron in the 5' untranslated region 6 nucleotides upstream from the initiator ATG, and 4 Introns 1n the coding region at codons specifying amino acids 41/42, 121/122, 267, and 327/328. Unlike the skeletal muscle actin gene and many other actin genes, the 6-act1n gene lacks the codon for Cys between the Initiator ATG and the codon for the N-terminal amino acid of the mature protein.The usage of synonymous codons 1n the β-actin gene is nonrandom, and is similar to that in the rat skeletal muscle and other vertebrate actin genes, but differs from the codon usage in yeast and soybean actin genes. © 1983 IRL Press Limited.
Note:
Related Files :
Animal
Base Sequence
cattle
Codon
conformation
Genetics
muscle
restriction endonuclease
structural gene
Show More
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More details
DOI :
10.1093/nar/11.6.1759
Article number:
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
29357
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:46
Scientific Publication
The nucleotide sequence of the rat cytoplasmic β-actin gene
11
Nudel, U., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Zakut, R., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Shani, M., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Neuman, S., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Levy, Z., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
Yaffe, D., Department of Cell Biology, Weizman Institute of Science, Rehovot, 76100, Israel
The nucleotide sequence of the rat cytoplasmic β-actin gene
The nucleotide sequence of the rat β-actin gene was determined. The gene codes for a protein identical to the bovine β-actin. It has a large intron in the 5' untranslated region 6 nucleotides upstream from the initiator ATG, and 4 Introns 1n the coding region at codons specifying amino acids 41/42, 121/122, 267, and 327/328. Unlike the skeletal muscle actin gene and many other actin genes, the 6-act1n gene lacks the codon for Cys between the Initiator ATG and the codon for the N-terminal amino acid of the mature protein.The usage of synonymous codons 1n the β-actin gene is nonrandom, and is similar to that in the rat skeletal muscle and other vertebrate actin genes, but differs from the codon usage in yeast and soybean actin genes. © 1983 IRL Press Limited.
Scientific Publication
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