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אסיף מאגר המחקר החקלאי
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Differential protective effects of antioxidants against cell killing and mutagenesis of Salmonella typhimurium by γ radiation
Year:
1981
Source of publication :
Journal of Radiation Research
Authors :
Rosenthal, Ionel
;
.
Volume :
22
Co-Authors:
Ben-Hur, E., Nucl. Res. Cent.-Negev, Beer-Sheva, Israel
Green, M., Nucl. Res. Cent.-Negev, Beer-Sheva, Israel
Prager, A., Nucl. Res. Cent.-Negev, Beer-Sheva, Israel
Rosenthal, I.
Riklis, E.
Facilitators :
From page:
250
To page:
257
(
Total pages:
8
)
Abstract:
A commercial mixture of phenolic antioxidants containing BHA, BHT and PG, commonly used in the food industry, was found to protect Salmonella typhimurium against killing and induction of his+ mutations by γ radiation. The protective effect was apparent only when irradiation was performed in the presence of oxygen and no protection could be detected in its absence. When each of the components of the antioxidant mixture was tested separately, only PG displayed a protective effect. The amount of protection provided by the mixture of antioxidants was close to the protection afforded by hypoxia. Also, protection against cell killing was very similar in magnitude to protection against induction of mutations. The protective effect could be detected only when antioxidants were added to the cells before irradiation. No protection was afforded upon additon immediately after irradiation.
Note:
Related Files :
animal experiment
antioxidants
butylated hydroxyanisole
gallic acid propyl ester
gamma radiation
Heredity
mutation
Show More
Related Content
More details
DOI :
Article number:
0
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
29909
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:50
Scientific Publication
Differential protective effects of antioxidants against cell killing and mutagenesis of Salmonella typhimurium by γ radiation
22
Ben-Hur, E., Nucl. Res. Cent.-Negev, Beer-Sheva, Israel
Green, M., Nucl. Res. Cent.-Negev, Beer-Sheva, Israel
Prager, A., Nucl. Res. Cent.-Negev, Beer-Sheva, Israel
Rosenthal, I.
Riklis, E.
Differential protective effects of antioxidants against cell killing and mutagenesis of Salmonella typhimurium by γ radiation
A commercial mixture of phenolic antioxidants containing BHA, BHT and PG, commonly used in the food industry, was found to protect Salmonella typhimurium against killing and induction of his+ mutations by γ radiation. The protective effect was apparent only when irradiation was performed in the presence of oxygen and no protection could be detected in its absence. When each of the components of the antioxidant mixture was tested separately, only PG displayed a protective effect. The amount of protection provided by the mixture of antioxidants was close to the protection afforded by hypoxia. Also, protection against cell killing was very similar in magnitude to protection against induction of mutations. The protective effect could be detected only when antioxidants were added to the cells before irradiation. No protection was afforded upon additon immediately after irradiation.
Scientific Publication
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