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The inhibitive effects of azasterols on sterol metabolism and growth and development in insects with special reference to the tobacco hornworm
Year:
1971
Source of publication :
Lipids
Authors :
Svoboda, James
;
.
Volume :
6
Co-Authors:
Svoboda, J.A., Insect Physiology Laboratory, Entomology Research Division, U.S. Dept. of Agriculture, Beltsville, 20705, Maryland, United States
Robbins, W.E., Insect Physiology Laboratory, Entomology Research Division, U.S. Dept. of Agriculture, Beltsville, 20705, Maryland, United States
Facilitators :
From page:
113
To page:
119
(
Total pages:
7
)
Abstract:
Several monoazasterols were found to be potent inhibitors of Δ24- and Δ22,24- reductase enzyme(s) in the tobacco hornworm, Manduca sexta (Johannson). Certain of these inhibitors also prevented normal larval development and pupation in the hornworm at dietary concentrations in the parts per million range. Comparative studies with several different insects indicated differences between the species with respect to the effects of the azasterols. The relationship of azasterol structure to the inhibitory effect(s) on sterol metabolism and larval development is discussed. © 1971 American Oil Chemists' Society.
Note:
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More details
DOI :
10.1007/BF02531326
Article number:
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
30747
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:56
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Scientific Publication
The inhibitive effects of azasterols on sterol metabolism and growth and development in insects with special reference to the tobacco hornworm
6
Svoboda, J.A., Insect Physiology Laboratory, Entomology Research Division, U.S. Dept. of Agriculture, Beltsville, 20705, Maryland, United States
Robbins, W.E., Insect Physiology Laboratory, Entomology Research Division, U.S. Dept. of Agriculture, Beltsville, 20705, Maryland, United States
The inhibitive effects of azasterols on sterol metabolism and growth and development in insects with special reference to the tobacco hornworm
Several monoazasterols were found to be potent inhibitors of Δ24- and Δ22,24- reductase enzyme(s) in the tobacco hornworm, Manduca sexta (Johannson). Certain of these inhibitors also prevented normal larval development and pupation in the hornworm at dietary concentrations in the parts per million range. Comparative studies with several different insects indicated differences between the species with respect to the effects of the azasterols. The relationship of azasterol structure to the inhibitory effect(s) on sterol metabolism and larval development is discussed. © 1971 American Oil Chemists' Society.
Scientific Publication
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