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Differential stress responses among newly received calves: Variations in reductant capacity and Hsp gene expression
Year:
2010
Source of publication :
Cell Stress and Chaperones
Authors :
Brosh, Arieh
;
.
Eitam, Harel
;
.
Orlov, Alla V.
;
.
Shabtay, Ariel
;
.
Volume :
15
Co-Authors:
Eitam, H., Department of Ruminant Science and Genetics, Institute of Animal Science, Agricultural Research Organization, P.O. Box 1021, Ramat Yishay 30095, Israel, Department of Evolutionary and Environmental Biology, Faculty of Science and Science Education, University of Haifa, Tivon 31905, Israel
Vaya, J., Migal, Galilee Technological Center, Kiryat Shmona 10200, Israel
Brosh, A., Department of Ruminant Science and Genetics, Institute of Animal Science, Agricultural Research Organization, P.O. Box 1021, Ramat Yishay 30095, Israel
Orlov, A., Department of Ruminant Science and Genetics, Institute of Animal Science, Agricultural Research Organization, P.O. Box 1021, Ramat Yishay 30095, Israel
Khatib, S., Migal, Galilee Technological Center, Kiryat Shmona 10200, Israel
Izhaki, I., Department of Evolutionary and Environmental Biology, Faculty of Science and Science Education, University of Haifa, Tivon 31905, Israel
Shabtay, A., Department of Ruminant Science and Genetics, Institute of Animal Science, Agricultural Research Organization, P.O. Box 1021, Ramat Yishay 30095, Israel
Facilitators :
From page:
865
To page:
876
(
Total pages:
12
)
Abstract:
Bovine respiratory disease complex (BRD), a major economic concern to the beef cattle industry all over the world, is triggered by physical, biological and psychological stresses. It is becoming noticeable that the key to reducing BRD appears to be centered at reducing the response to stress. The aims of the present study were to detect individual variations in the stress response of newly received young calves through their leukocyte heat shock protein (Hsp) response, selected neutrophil-related gene expression and oxidative stress, and relate them to pulmonary adhesions at slaughter, an indicative sign of clinical and subclinical episodes of BRD at an early age. Differential expression patterns of Hsp60 and Hsp70A1A were revealed in newly received calves 1 h, 5 h and 1 day after arrival, distinguishing between stress-responsive and non-stress-responsive individuals. Plasma cortisol was also indicative of stress-responsive and non-stress-responsive individuals, 1 h and 5 h after arrival. At the longer term, β-glycan levels were highest 7 days after arrival and significantly correlated with an adhesion-free phenotype at slaughter. Oxidative stress responses, measured through the oxidation products of the exogenous linoleoyl tyrosine (LT) marker, revealed that hydroperoxidation and epoxidation of membranes may readily occur. Based on the LT oxidation products and levels of β-glycan, we present a discriminant analysis model, according to which vulnerable individuals may be predicted at near 100% probability 7 days after arrival. Since clinical signs of BRD may often go undetected in feedlot calves, such a model, after its examination in large-scale experiments, may be a reliable tool for an early prediction of subclinical signs of BRD. © 2010 Cell Stress Society International.
Note:
Related Files :
animal experiment
Animals
animal tissue
calf (bovine)
cattle
genetic susceptibility
Linoleic Acids
oxidation
stress
Show More
Related Content
More details
DOI :
10.1007/s12192-010-0195-9
Article number:
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
30979
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:58
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