Shamay, A., Agricultural Research Organization (ARO), The Volcani Center, Institute of Animal Science, P.O. Box 6, Bet Dagan 50250, Israel
Mabjeesh, S.J., Agricultural Research Organization (ARO), The Volcani Center, Institute of Animal Science, P.O. Box 6, Bet Dagan 50250, Israel
Shapiro, F., Agricultural Research Organization (ARO), The Volcani Center, Institute of Animal Science, P.O. Box 6, Bet Dagan 50250, Israel
Silanikove, N., Agricultural Research Organization (ARO), The Volcani Center, Institute of Animal Science, P.O. Box 6, Bet Dagan 50250, Israel

The ability of adrenocorticotrophic hormone (ACTH; single i.v. injection of 2.5 IU/kg BW) and dexamethasone (single i.m. injection of 36 mg/kg BW) to affect milk production was studied in mid-lactating Israeli Saanen goats. None of these treatments produced changes in milk yield and composition of the goats. The effects of ACTH on blood cortisol levels, and the effects of ACTH and dexamethasone on blood plasma concentrations of glucose, however, were consistent with previous reports in goats and cows. These responses suggest that ACTH and dexamethasone treatments produced their expected glucocorticoid effects. It is suggested that obstructing the axis: Stress-ACTH-glucocorticoid-down regulation of milk yield, which was demonstrated in dairy cows, reflects the adaptation of goats to harsh conditions, and the selection pressure to produce milk under conditions which are considered stressful for other ruminants. © 2000 Elsevier Science B.V.