נגישות
menu      
Advanced Search
Syntax
Search...
Volcani treasures
About
Terms of use
Manage
Community:
אסיף מאגר המחקר החקלאי
Powered by ClearMash Solutions Ltd -
A galactopoeitic role for oxytocin in the cow
Year:
1967
Source of publication :
Life Sciences
Authors :
Morag, M.
;
.
Volume :
6
Co-Authors:
Morag, M., University of Reading, England, United Kingdom
Facilitators :
From page:
1513
To page:
1516
(
Total pages:
4
)
Abstract:
The effects of cardiac glycosides, a group of synthetic azasteroids, and erythropheleum alkaloids upon a transport ATPase activity of ciliary processes of rabbit eyes have been studied. All three groups of compounds effectively inhibited the metal-stimulated ATPase activity. The physiological, biochemical, and general chemical similarities of these three classes of compounds make it possible, with careful reservation, to group them together for the adduction of the structural requirements for this pattern of inhibition of the ciliary process enzyme. Quindonium, quinolizinium, and methyl quinolizinium were quite similar to ouabain in their effects. The B isomer quindonium inhibited to a lesser degree while the erythrophleum alkaloids, though highly effective, were insensitive to preparative methods which affected membrane integrity. These results have been discussed with respect to structure-activity relationships, the mechanism of aqueous humor ecretion, and possible use of the azasteroids as ophthalmic drugs. © 1967.
Note:
Related Files :
Animal
article
cattle
drug effect
Female
lactation
Mammae
milk
oxytocin
pregnancy
secretion
Secretory Rate
Show More
Related Content
More details
DOI :
Article number:
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
31913
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 01:06
Scientific Publication
A galactopoeitic role for oxytocin in the cow
6
Morag, M., University of Reading, England, United Kingdom
A galactopoeitic role for oxytocin in the cow
The effects of cardiac glycosides, a group of synthetic azasteroids, and erythropheleum alkaloids upon a transport ATPase activity of ciliary processes of rabbit eyes have been studied. All three groups of compounds effectively inhibited the metal-stimulated ATPase activity. The physiological, biochemical, and general chemical similarities of these three classes of compounds make it possible, with careful reservation, to group them together for the adduction of the structural requirements for this pattern of inhibition of the ciliary process enzyme. Quindonium, quinolizinium, and methyl quinolizinium were quite similar to ouabain in their effects. The B isomer quindonium inhibited to a lesser degree while the erythrophleum alkaloids, though highly effective, were insensitive to preparative methods which affected membrane integrity. These results have been discussed with respect to structure-activity relationships, the mechanism of aqueous humor ecretion, and possible use of the azasteroids as ophthalmic drugs. © 1967.
Scientific Publication
You may also be interested in