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Induction of oral tolerance prior to or following bone marrow transplantation ameliorates chronic graft versus host disease in a murine model [abstract]
Year:
2000
Source of publication :
Gastroenterology (journal)Authors :
Pines, Mark
;
.
Volume :
118, issue 4, part 1
Co-Authors:
Israel Gotsman, Arnon Nagler, Roy Beinart, Uri Abadi, Elazar, Rabbani, Dean Engelhardt, Yaron Ilan
Facilitators :
From page:
0
To page:
0
(
Total pages:
1
)
Abstract:
Background: In chronic graft versus host disease (cGVHD) an immune attack by
transplanted donor lymphocytes results in inflammatory damage. Immune
hyporesponsiveness induced by oral antigen administration has been shown to suppress
immune-mediated-disorders. Aim: To evaluate the efficacy on cGVHD of oral tolerization
prior to or following transplantation. Methods: cGVHD was generated by infusing 2.5 xlO
splenocytes from BIO. D2 donor mice, to sublethally irradiated (6Gy) Balb/C recipient mice …
Note:
P. A357
Related Files :
bone marrow transplantation
chronic graft versus host disease
immune system
Mice models
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DOI :
Article number:
0
Affiliations:
Database:
Google Scholar
Publication Type:
Abstract
;
.
Conference paper
;
.
Language:
English
Editors' remarks:
ID:
38131
Last updated date:
02/03/2022 17:27
Creation date:
25/11/2018 09:06
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