תפריט נגישות
ניגודיות עדינהניגודיות גבוהה
מונוכרום
הדגשת קישורים
חסימת אנימציה
פונט קריא
סגור
איפוס הגדרות נגישות
להורדת מודול נגישות חינם תפריט נגישותניגודיות עדינהניגודיות גבוההמונוכרוםהדגשת קישוריםחסימת אנימציהפונט קריאסגוראיפוס הגדרות נגישותלהורדת מודול נגישות חינםRohit Kumar Tiwari - Department of Biosciences, Integral University, Kursi Road, Lucknow, Uttar Pradesh, 226026, India.
Sarika Singh - Division of Toxicology, CSIR-Central Drug Research Institute, B.S. 10/1, Sector-10, Jankipuram Extension, Lucknow, Uttar Pradesh, 226031, India.
Chhedi Lal Gupta - Institute of Soil, Water and Environmental Sciences, Volcani Research Center, ARO, 68 HaMacabim Rd, P.O Box 15159, 7528809, Rishon Lezion, Israel.
Preeti Bajpai - Department of Biosciences, Integral University, Kursi Road, Lucknow, Uttar Pradesh, 226026, India; Department of Zoology, Mahatma Gandhi Central University, Motihari, East Champaran, Bihar, 845401, India.
An understanding of pattern recognition receptors (PRRs) and immunomodulatory approach based on activation of these receptors has provided insights critical for the management of neurological health disorders. Toll-like receptors (TLRs) are one of the most widely explored PRRs and have been exploited in the recent past for development of novel immunomodulatory therapeutic agents. Glioblastoma multiforme is characterized by significant infiltration of resident microglia and expresses all the members of the TLR family. The present report is focused on exciting findings pertaining to probable implications of TLR9 activation by unmethylated CG sequences for novel therapeutic intervention against glioblastoma multiforme, which could be a discrete step toward the effective management of neurological health issues.
Rohit Kumar Tiwari - Department of Biosciences, Integral University, Kursi Road, Lucknow, Uttar Pradesh, 226026, India.
Sarika Singh - Division of Toxicology, CSIR-Central Drug Research Institute, B.S. 10/1, Sector-10, Jankipuram Extension, Lucknow, Uttar Pradesh, 226031, India.
Chhedi Lal Gupta - Institute of Soil, Water and Environmental Sciences, Volcani Research Center, ARO, 68 HaMacabim Rd, P.O Box 15159, 7528809, Rishon Lezion, Israel.
Preeti Bajpai - Department of Biosciences, Integral University, Kursi Road, Lucknow, Uttar Pradesh, 226026, India; Department of Zoology, Mahatma Gandhi Central University, Motihari, East Champaran, Bihar, 845401, India.
An understanding of pattern recognition receptors (PRRs) and immunomodulatory approach based on activation of these receptors has provided insights critical for the management of neurological health disorders. Toll-like receptors (TLRs) are one of the most widely explored PRRs and have been exploited in the recent past for development of novel immunomodulatory therapeutic agents. Glioblastoma multiforme is characterized by significant infiltration of resident microglia and expresses all the members of the TLR family. The present report is focused on exciting findings pertaining to probable implications of TLR9 activation by unmethylated CG sequences for novel therapeutic intervention against glioblastoma multiforme, which could be a discrete step toward the effective management of neurological health issues.
