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Extracellular resveratrol producing endophytic fungus, Quambalaria cyanescens
Year:
2021
Source of publication :
South African Journal of Botany
Authors :
Meshram, Vineet
;
.
Volume :
146
Co-Authors:

Vineet Meshram
Neha Kapoor
Vagish Dwibedi
Anugya Srivastava
Sanjai Saxena

Facilitators :
From page:
409
To page:
416
(
Total pages:
8
)
Abstract:

A fungal endophyte of Vitis vinifera, Quambalaria cyanescens is shown to produce high amount of resveratrol, a well-known anti-cancer agent in culture media. The ethyl acetate extract of the crude culture filtrate yielded 240 mg of which 40 mg of purified Resveratrol was recovered. The endophyte is first of its kind to be reported from Vitis vinifera, and was identified by taxonomic and molecular phylogenetic methods. The fungal resveratrol exhibited a potent cytotoxic activity against A549, with 82% reduction in the cell count. It also exhibited a potent anti-oxidant activity with 83% radical scavenging activity. Further, the fungal resveratrol from Q. cyanescens also exhibited a potent activity against methicillin resistant Staphylococcus aureus. Thus, this endophytic Quambalaria cyanescens holds a promise for development into a commercial strain for fermentative production of resveratrol.

Note:
Related Files :
Anti-oxidant activity
Anti-tumor activity
ITS-rDNA
Quambalaria cyanescens
Vitis vinifera
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Related Content
More details
DOI :
10.1016/j.sajb.2021.11.026
Article number:
0
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
57230
Last updated date:
02/03/2022 17:27
Creation date:
19/12/2021 17:17
Scientific Publication
Extracellular resveratrol producing endophytic fungus, Quambalaria cyanescens
146

Vineet Meshram
Neha Kapoor
Vagish Dwibedi
Anugya Srivastava
Sanjai Saxena

Extracellular resveratrol producing endophytic fungus, Quambalaria cyanescens .

A fungal endophyte of Vitis vinifera, Quambalaria cyanescens is shown to produce high amount of resveratrol, a well-known anti-cancer agent in culture media. The ethyl acetate extract of the crude culture filtrate yielded 240 mg of which 40 mg of purified Resveratrol was recovered. The endophyte is first of its kind to be reported from Vitis vinifera, and was identified by taxonomic and molecular phylogenetic methods. The fungal resveratrol exhibited a potent cytotoxic activity against A549, with 82% reduction in the cell count. It also exhibited a potent anti-oxidant activity with 83% radical scavenging activity. Further, the fungal resveratrol from Q. cyanescens also exhibited a potent activity against methicillin resistant Staphylococcus aureus. Thus, this endophytic Quambalaria cyanescens holds a promise for development into a commercial strain for fermentative production of resveratrol.

Scientific Publication
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