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Illuminating the Molecular Intricacies of Exosomes and ncRNAs in Cardiovascular Diseases: Prospective Therapeutic and Biomarker Potential
Year:
2022
Source of publication :
Cells
Authors :
Daddam, Jayasimha Rayalu
;
.
Volume :
Co-Authors:

Farheen Badrealam Khan
Shahab Uddin
Abozer Y Elderdery
Khang Wen Goh 
Long Chiau Ming 
Chrismawan Ardianto
Abdul Rasheed Palakot
Irfa Anwar
Mohsina Khan
Mohammad Owais
Chih-Yang Huang
Jayasimha Rayalu Daddam
Meraj Alam Khan
Shoaib Shoaib
Md Khursheed 
Sara Reshadat 
Hamid Reza Khayat Kashani
Sameer Mirza 
Abbas A Khaleel
Mohammed Akli Ayoub

Facilitators :
From page:
0
To page:
0
(
Total pages:
1
)
Abstract:

Cardiovascular diseases (CVDs) are one of the leading causes of death worldwide. Accumulating evidences have highlighted the importance of exosomes and non-coding RNAs (ncRNAs) in cardiac physiology and pathology. It is in general consensus that exosomes and ncRNAs play a crucial role in the maintenance of normal cellular function; and interestingly it is envisaged that their potential as prospective therapeutic candidates and biomarkers are increasing rapidly. Considering all these aspects, this review provides a comprehensive overview of the recent understanding of exosomes and ncRNAs in CVDs. We provide a great deal of discussion regarding their role in the cardiovascular system, together with providing a glimpse of ideas regarding strategies exploited to harness their potential as a therapeutic intervention and prospective biomarker against CVDs. Thus, it could be envisaged that a thorough understanding of the intricacies related to exosomes and ncRNA would seemingly allow their full exploration and may lead clinical settings to become a reality in near future.

Note:
Related Files :
cardiovascular disease
circRNA
exosome
lncRNA
miRNA
ncRNA
Show More
Related Content
More details
DOI :
10.3390/cells11223664
Article number:
0
Affiliations:
Database:
PubMed
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
62552
Last updated date:
28/11/2022 17:07
Creation date:
28/11/2022 17:07
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Scientific Publication
Illuminating the Molecular Intricacies of Exosomes and ncRNAs in Cardiovascular Diseases: Prospective Therapeutic and Biomarker Potential

Farheen Badrealam Khan
Shahab Uddin
Abozer Y Elderdery
Khang Wen Goh 
Long Chiau Ming 
Chrismawan Ardianto
Abdul Rasheed Palakot
Irfa Anwar
Mohsina Khan
Mohammad Owais
Chih-Yang Huang
Jayasimha Rayalu Daddam
Meraj Alam Khan
Shoaib Shoaib
Md Khursheed 
Sara Reshadat 
Hamid Reza Khayat Kashani
Sameer Mirza 
Abbas A Khaleel
Mohammed Akli Ayoub

Illuminating the Molecular Intricacies of Exosomes and ncRNAs in Cardiovascular Diseases: Prospective Therapeutic and Biomarker Potential

Cardiovascular diseases (CVDs) are one of the leading causes of death worldwide. Accumulating evidences have highlighted the importance of exosomes and non-coding RNAs (ncRNAs) in cardiac physiology and pathology. It is in general consensus that exosomes and ncRNAs play a crucial role in the maintenance of normal cellular function; and interestingly it is envisaged that their potential as prospective therapeutic candidates and biomarkers are increasing rapidly. Considering all these aspects, this review provides a comprehensive overview of the recent understanding of exosomes and ncRNAs in CVDs. We provide a great deal of discussion regarding their role in the cardiovascular system, together with providing a glimpse of ideas regarding strategies exploited to harness their potential as a therapeutic intervention and prospective biomarker against CVDs. Thus, it could be envisaged that a thorough understanding of the intricacies related to exosomes and ncRNA would seemingly allow their full exploration and may lead clinical settings to become a reality in near future.

Scientific Publication
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