נגישות
menu      
Advanced Search
Syntax
Search...
Volcani treasures
About
Terms of use
Manage
Community:
אסיף מאגר המחקר החקלאי
Powered by ClearMash Solutions Ltd -
Small GTPases RasA and RasB regulate development, patulin production, and virulence of Penicillium expansum
Year:
2023
Source of publication :
Postharvest Biology and Technology
Authors :
Prusky, Dov
;
.
Sionov, Edward
;
.
Volume :
197
Co-Authors:

Yuanyuan Zong
Xuemei Zhang
Di Gong
Feng Zhang
Lirong Yu
Yang Bi
Edward Sionov
Dov Prusky

Facilitators :
From page:
0
To page:
0
(
Total pages:
1
)
Abstract:

Ras GTPases belong to one of the small G proteins, which regulate morphology and growth of filamentous fungi. However, whether Ras GTPases are involved in the biological process of Penicillium expansum remains unclear. In this study, RasA and RasB gene knockout mutants of P. expansum were constructed. ΔPeRasA and ΔPeRasB showed defective growth, insufficient spore development and malformed mycelium. Loss of PeRasA and PeRasB resulted in a markedly reduction of patulin content and a down-regulation genes expression involved in patulin biosynthesis. Deletion of PeRasA and PeRasB significantly down-regulated the expression of MAPK and cAMP signal regulators. Additionally, ΔPeRasA and ΔPeRasB exhibited attenuated virulence on apple and pear fruit and lower gene expression of cell wall degrading enzymes. In summary, PeRasA and PeRasB were involved in the development, patulin synthesis and virulence of P. expansum by controlling MAPK and cAMP signaling pathways.

Note:
Related Files :
Development
Fruits
patulin
Penicillium expansum
Ras GTPases
virulence
Show More
Related Content
More details
DOI :
10.1016/j.postharvbio.2022.112192
Article number:
112192
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
62581
Last updated date:
04/12/2022 16:24
Creation date:
04/12/2022 16:23
You may also be interested in
Scientific Publication
Small GTPases RasA and RasB regulate development, patulin production, and virulence of Penicillium expansum
197

Yuanyuan Zong
Xuemei Zhang
Di Gong
Feng Zhang
Lirong Yu
Yang Bi
Edward Sionov
Dov Prusky

Small GTPases RasA and RasB regulate development, patulin production, and virulence of Penicillium expansum

Ras GTPases belong to one of the small G proteins, which regulate morphology and growth of filamentous fungi. However, whether Ras GTPases are involved in the biological process of Penicillium expansum remains unclear. In this study, RasA and RasB gene knockout mutants of P. expansum were constructed. ΔPeRasA and ΔPeRasB showed defective growth, insufficient spore development and malformed mycelium. Loss of PeRasA and PeRasB resulted in a markedly reduction of patulin content and a down-regulation genes expression involved in patulin biosynthesis. Deletion of PeRasA and PeRasB significantly down-regulated the expression of MAPK and cAMP signal regulators. Additionally, ΔPeRasA and ΔPeRasB exhibited attenuated virulence on apple and pear fruit and lower gene expression of cell wall degrading enzymes. In summary, PeRasA and PeRasB were involved in the development, patulin synthesis and virulence of P. expansum by controlling MAPK and cAMP signaling pathways.

Scientific Publication
You may also be interested in