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קהילה:
אסיף מאגר המחקר החקלאי
פותח על ידי קלירמאש פתרונות בע"מ -
Fetal abnormalities leading to termination of pregnancy: The experience at the Assaf Harofeh medical center between the years 1999-2000
Year:
2003
Source of publication :
Harefuah
Authors :
שרון, מיכל
;
.
Volume :
142
Co-Authors:
Maymon, R.
Sharon, M.
Reish, O.
Schneider, D.
Halperin, R.
Herman, A.
Facilitators :
From page:
405
To page:
(
Total pages:
-404
)
Abstract:
Objectives: To assess the distribution of fetal indications leading to termination of pregnancy. Design: A retrospective study. Methods: The study included all parturient women with singleton pregnancy, who underwent termination of pregnancy due to fetal abnormalities (structural, chromosomal/genetic, infections). The women were subdivided into two groups according to their gestational age, i.e. early termination (gestational period < 23 weeks) and late termination (gestational period > 23 weeks) Results: A total of 137 terminations of pregnancies were performed, including 102 early terminations and the rest - late terminations. The mean maternal age was 31 ± 5 years. The termination procedures were performed at a mean gestational age of 20 ± 5 weeks. The main indications in the early-termination subgroup were structural and chromosomal/genetic (n = 45, 44% for each subgroup). Multiple abnormalities were more common in the early-termination group (18% versus 7%). In the late-termination subgroup the leading indications were structural anomalies (n = 29, 83%) that were subdivided into neurological defects (31%) followed by skeletal deformities (23%). In addition, in the late-termination subgroup there were more cardiac and urinary tract defects (17% versus 11% and 14% versus 9%, respectively). Among the chromosomal aneuploidies, trisomy 21 was diagnosed in 24 cases (53%). Fetal infections were diagnosed in 13 pregnancies (9%), with only one of these detected in advanced gestation. The leading infectious agent was cytomegalovirus. Conclusions: In the early-termination subgroup the main indications were equally divided between structural and chromosomal/genetic defects while in the late-termination subgroup the leading cause was structural defects.
Note:
Related Files :
adult
Female
Fetal infection
fetus disease
Israel
pregnancy
retrospective study
עוד תגיות
תוכן קשור
More details
DOI :
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
עברית
Editors' remarks:
ID:
27574
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:32
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Scientific Publication
Fetal abnormalities leading to termination of pregnancy: The experience at the Assaf Harofeh medical center between the years 1999-2000
142
Maymon, R.
Sharon, M.
Reish, O.
Schneider, D.
Halperin, R.
Herman, A.
Fetal abnormalities leading to termination of pregnancy: The experience at the Assaf Harofeh medical center between the years 1999-2000
Objectives: To assess the distribution of fetal indications leading to termination of pregnancy. Design: A retrospective study. Methods: The study included all parturient women with singleton pregnancy, who underwent termination of pregnancy due to fetal abnormalities (structural, chromosomal/genetic, infections). The women were subdivided into two groups according to their gestational age, i.e. early termination (gestational period < 23 weeks) and late termination (gestational period > 23 weeks) Results: A total of 137 terminations of pregnancies were performed, including 102 early terminations and the rest - late terminations. The mean maternal age was 31 ± 5 years. The termination procedures were performed at a mean gestational age of 20 ± 5 weeks. The main indications in the early-termination subgroup were structural and chromosomal/genetic (n = 45, 44% for each subgroup). Multiple abnormalities were more common in the early-termination group (18% versus 7%). In the late-termination subgroup the leading indications were structural anomalies (n = 29, 83%) that were subdivided into neurological defects (31%) followed by skeletal deformities (23%). In addition, in the late-termination subgroup there were more cardiac and urinary tract defects (17% versus 11% and 14% versus 9%, respectively). Among the chromosomal aneuploidies, trisomy 21 was diagnosed in 24 cases (53%). Fetal infections were diagnosed in 13 pregnancies (9%), with only one of these detected in advanced gestation. The leading infectious agent was cytomegalovirus. Conclusions: In the early-termination subgroup the main indications were equally divided between structural and chromosomal/genetic defects while in the late-termination subgroup the leading cause was structural defects.
Scientific Publication
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