נגישות
menu      
Advanced Search
Syntax
Search...
Volcani treasures
About
Terms of use
Manage
Community:
אסיף מאגר המחקר החקלאי
Powered by ClearMash Solutions Ltd -
The concordance test emerges as a powerful tool for identifying quantitative trait nucleotides: Lessons from BTA6 milk yield QTL
Year:
2009
Source of publication :
Animal Genetics
Authors :
Seroussi, Eyal
;
.
Volume :
40
Co-Authors:
Seroussi, E., Agricultural Research Organization, Institute of Animal Science, Bet-Dagan 50250, Israel, Institute of Animal Science, ARO, Volcani Center, Bet-Dagan 50250, Israel
Facilitators :
From page:
230
To page:
234
(
Total pages:
5
)
Abstract:
The lack of conventions for confirming the discovery of quantitative trait nucleotides in livestock was evidenced by the proposals of mutations in two different genes (SPP1 and ABCG2) as the underlying functional mutation for a major quantitative trait locus (QTL) for milk concentration on bovine chromosome 6 (BTA6). Of these conflicting candidates, SPP1 was excluded by follow-up studies and by the data described here. A simple test for concordance of the zygosity state between QTL segregation status and the candidate polymorphism was shown, in this case, to be a critical step towards establishing the proof. If a given sample effectively represents the genetic variation across the QTL region, haplotype-based concordance may further enhance the functionality and resolution power of this test, allowing identification of the causative gene. © 2008 The Author.
Note:
Related Files :
Animals
cattle
Female
Genetics
milk
Show More
Related Content
More details
DOI :
10.1111/j.1365-2052.2008.01809.x
Article number:
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
25782
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:17
You may also be interested in
Scientific Publication
The concordance test emerges as a powerful tool for identifying quantitative trait nucleotides: Lessons from BTA6 milk yield QTL
40
Seroussi, E., Agricultural Research Organization, Institute of Animal Science, Bet-Dagan 50250, Israel, Institute of Animal Science, ARO, Volcani Center, Bet-Dagan 50250, Israel
The concordance test emerges as a powerful tool for identifying quantitative trait nucleotides: Lessons from BTA6 milk yield QTL
The lack of conventions for confirming the discovery of quantitative trait nucleotides in livestock was evidenced by the proposals of mutations in two different genes (SPP1 and ABCG2) as the underlying functional mutation for a major quantitative trait locus (QTL) for milk concentration on bovine chromosome 6 (BTA6). Of these conflicting candidates, SPP1 was excluded by follow-up studies and by the data described here. A simple test for concordance of the zygosity state between QTL segregation status and the candidate polymorphism was shown, in this case, to be a critical step towards establishing the proof. If a given sample effectively represents the genetic variation across the QTL region, haplotype-based concordance may further enhance the functionality and resolution power of this test, allowing identification of the causative gene. © 2008 The Author.
Scientific Publication
You may also be interested in