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Arrest of host DNA synthesis in Bacillus subtilis infected with phage ∅e
Year:
1972
Source of publication :
Virology
Authors :
Lavi, Uri
;
.
Volume :
49
Co-Authors:
Lavi, U., Department of Genetics, The Hebrew University, Jerusalem, Israel
Marcus, M., Department of Genetics, The Hebrew University, Jerusalem, Israel
Facilitators :
From page:
668
To page:
674
(
Total pages:
7
)
Abstract:
Arrest of host DNA synthesis in Bacillus subtilis infected with the virulent phage ∅e is dependent on the synthesis of a phage-coded protein (Marcus and Newlon, 1971). The mechanism of host DNA arrest was studied in toluene-treated B. subtilis cells. The results showed that preparations of toluenized phage infected cells manifest faithfully the kinetics and specificity of host DNA arrest and the appearance of phage DNA synthesis. The arrest of host DNA synthesis is not caused by the production in the host DNA of single strand breaks that can be repaired by the DNA polymerase repair enzyme (Pol I). Neither hydroxymethyl deoxyuridylate (HMdUMP) nor probably any other small molecule is responsible for host DNA arrest. © 1972.
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More details
DOI :
10.1016/0042-6822(72)90523-5
Article number:
0
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
27018
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:27
Scientific Publication
Arrest of host DNA synthesis in Bacillus subtilis infected with phage ∅e
49
Lavi, U., Department of Genetics, The Hebrew University, Jerusalem, Israel
Marcus, M., Department of Genetics, The Hebrew University, Jerusalem, Israel
Arrest of host DNA synthesis in Bacillus subtilis infected with phage ∅e
Arrest of host DNA synthesis in Bacillus subtilis infected with the virulent phage ∅e is dependent on the synthesis of a phage-coded protein (Marcus and Newlon, 1971). The mechanism of host DNA arrest was studied in toluene-treated B. subtilis cells. The results showed that preparations of toluenized phage infected cells manifest faithfully the kinetics and specificity of host DNA arrest and the appearance of phage DNA synthesis. The arrest of host DNA synthesis is not caused by the production in the host DNA of single strand breaks that can be repaired by the DNA polymerase repair enzyme (Pol I). Neither hydroxymethyl deoxyuridylate (HMdUMP) nor probably any other small molecule is responsible for host DNA arrest. © 1972.
Scientific Publication
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